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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SMG6 All Species: 27.58
Human Site: S895 Identified Species: 67.41
UniProt: Q86US8 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86US8 NP_060045.4 1419 160462 S895 L N K R F I L S F L H A H G K
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_548319 1527 171816 S1003 L N K R F I L S F L H A H G K
Cat Felis silvestris
Mouse Mus musculus P61406 1418 160477 S894 L N K R F I L S F L H A H G K
Rat Rattus norvegicus NP_001099278 1472 165733 S948 L N K R F I L S F L H A H G K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509588 959 106964 E480 R L L E L L D E G T S F F D S
Chicken Gallus gallus XP_001234885 1419 159567 S927 L N K R F I L S F L H A H G K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_696418 1546 172554 S1012 L N K R F I L S F L H A H G K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651321 948 108473 L469 T G T D V D S L Y P L L R K L
Honey Bee Apis mellifera XP_393289 1688 192186 S1161 V N K R F V T S Y L H V H G K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_794411 1745 199805 S1208 P F V T A R E S L M T L F E E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 85.5 N.A. 90.8 88 N.A. 40.7 69.6 N.A. 49.3 N.A. 21.7 29.7 N.A. 24.4
Protein Similarity: 100 N.A. N.A. 88.7 N.A. 95.1 91.9 N.A. 49.8 80.3 N.A. 64.4 N.A. 36.2 45.5 N.A. 41.7
P-Site Identity: 100 N.A. N.A. 100 N.A. 100 100 N.A. 0 100 N.A. 100 N.A. 0 66.6 N.A. 6.6
P-Site Similarity: 100 N.A. N.A. 100 N.A. 100 100 N.A. 6.6 100 N.A. 100 N.A. 6.6 86.6 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 10 0 0 0 0 0 0 60 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 10 0 10 10 0 0 0 0 0 0 10 0 % D
% Glu: 0 0 0 10 0 0 10 10 0 0 0 0 0 10 10 % E
% Phe: 0 10 0 0 70 0 0 0 60 0 0 10 20 0 0 % F
% Gly: 0 10 0 0 0 0 0 0 10 0 0 0 0 70 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 70 0 70 0 0 % H
% Ile: 0 0 0 0 0 60 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 70 0 0 0 0 0 0 0 0 0 0 10 70 % K
% Leu: 60 10 10 0 10 10 60 10 10 70 10 20 0 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % M
% Asn: 0 70 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 10 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 10 0 0 70 0 10 0 0 0 0 0 0 10 0 0 % R
% Ser: 0 0 0 0 0 0 10 80 0 0 10 0 0 0 10 % S
% Thr: 10 0 10 10 0 0 10 0 0 10 10 0 0 0 0 % T
% Val: 10 0 10 0 10 10 0 0 0 0 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 20 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _